Megazyme has received several prestigious business and export awards in Australia and Ireland, including:

Ireland

• 2010 AOAC International - Study Director of the Year awarded to Barry McCleary
• 2010 AOAC International - Collaborative Study of the Year awarded to Barry McCleary
• 2010 Bray & District Chamber Endeavour Awards 'Outstanding Large Business' (Winner)
• 2010 Barry McCleary awarded the Faculty Alumni Award for International Achievement by Sydney University
• 2009 AACCI Applied Research Award
• 2009 Small Firms Association, National Business Awards 'Innovator of the Year' (Winner)
• 2008 Barry McCleary awarded the Edith A. Christensen Award at the AACC International Annual Meeting in Honolulu, Hawaii in September 2008
• 2008 Barry McCleary awarded the Clyde H. Bailey Medal at the ICC 13th World Cereal and Bread Congress held in Madrid in June 2008.
• 2007 Small Firms Association, National Business Awards 'Innovator of the Year' (Winner)
• 2005 ICT Excellence Awards, 'Best E-Commerce Site - Private Sector' (Winner)
• 2002 Harvey W. Wiley Medal - Presented to Barry McCleary by AOAC International for "career achievements in the analytical chemistry"
• 2000 Eircom/Irish Independent E-Business of the Year 2000 (Overall Winner)
• 1998 DHL Export of the Year Award (Finalist) Dublin, Ireland.
  

Australia

• 1994 NSW New Exporter of the Year  (Overall Winner)
• 1993 Australian Small Business of the Year (Manufacturer with up to 100 employees)
• 1993 NSW, Small Business of the Year (Manufacturer with up to 100 employees)
• 1993 New South Wales Small Business of the Year (Overall Winner)